'The Arranger'    Gene Hackman  Oswald P Silkworth is the top Lieutenant in 'The Crime Syndicate'. Working directly for its leader, 'TheKingpin', he seeks to gain secrets of government weapons manufacturer Osborn Industries, in a bid to unseat Norman Osborn and gain control of the company.
Jason 'Jack' Macendale   Gabriel Byrne      Ex Navy seal, and CIA operative-turned underworld assassin, Macendale is the top "muscle" in The Syndicate.
'Silvermane' Christopher Walken        Sicilian Businessman and NY mobster, he negotiates to buy Octavius' WMD before a rival gang can.
'The Hammer'  Robert Deniro  a.k.a.'Hammerhead' is a gang leader who also seeks Octavius' weapon and control of the cities crime scene.

'Chameleon'       Gary Oldman  Former KGB agent, Dimitri Smerdyakov  is the steely calm lord of the Russian Mob, known for his undercover ablility and disguises.

'Kingpin'       aka 'The BIg Man.Little is known about the mysterious Boss of NY City Crime

Dr Farley Stillwell       Tim Robbins Colleague and rival of Curt Connors, Stillwell is a former student and master mof neogenetics. His intentions and methods are questionable



Villains/Enemies

 

 

The Rhino
Brock Lesnar

 

Real Name: Alexei Sytsevitch

Alias: Alex O'Hirn

Height: 6' 6

Weight: 710 lbs (with suit)

Birthplace: Hell's Kitchen

 A  second-generation Russian immigrant, thug/hitman and former prize-fighter who is recruited to don a battlesuit that enhances his already formidable strength and speed. His task is to perform special operations for The Syndicate and take out Spider-Man!

The brutish Rhino possesses superhuman strength, speed, endurance and a high degree of resistance to physical harm.

His polymer armor, analogous to rhinoceros hide, covers his entire body except his face. The costume is highly impervious to damage and extremes of temperature, and the two horns that project from the Rhino's forehead can dent 2-inch plate steel.

Eddie Brock                                                             David Boreanaz

Real Name: Edward Brock

Age: 29

Height: 6' 3

Weight: 230 lbs

Hair: dirty blonde

Eyes: brown

Place of birth: Brooklyn

 More of a rival; Brock, a proven photographer, is The Bugle's fair-haired boy. Handpicked by J. Jonah Jameson to be the youngest executive in company history, he is the head art director and managing editor for NOW Magazine. Eddie does not particularly care for Peter Parker.